Profile

Lu Ge A doctoral student in College of Acupuncture Moxibustion and Tuina, Nanjing University of Chinese Medicine, studying under Professor Shen Mei-hong, and majoring in the mechanism research of acupuncture and moxibustion in the prevention and treatment of ovarian-related diseases.
Publications:

• Ge Lu, Qian Wang, Zi-Jing Xie, Shang-Jie Liang, Hong-Xiao Li, Ling Shi, Qian Li, Jie Shen, Jie Cheng, Mei-Hong Shen. Moxibustion Ameliorates Ovarian Reserve in Rats by Mediating Nrf2/HO-1/NLRP3 Anti-Inflammatory Pathway[J]. Evidence-Based Complementary and Alternative Medicine, 2021 (2021) 8817858.
• LU Ge, XIE Zi-jing, WANG Qian, LI Qian, LI Hong-xiao, SHEN Mei-hong. Effect of Acupuncture on Serum Inflammatory Factors and Nrf2/HO-1/NLRP3 Signaling Pathway in the Hypo-ovarian Reserve Function Model Rats[J].Journal of Traditional Chinese Medcine, 2020,61(15):1350-1356.
  Project:
  The Postgraduate Research and Practice Innovation Program of Jiangsu Province (No. KYCX20_1541)
• Lu G, Zhu YY, Li HX, Yin YL, Shen J, Shen MH. Effects of acupuncture treatment on microRNAs expression in ovarian tissues from Tripterygium glycoside-induced diminished ovarian reserve rats. Front Genet. 2022;13:968711.

Abstract

Chemotherapy is one of the common causes of ovarian function damage. Women who accept chemotherapy at reproductive age face high risks of ovarian reserve damage. Acupuncture and moxibustion, which as a form of traditional Chinese medicine therapy, has significant clinical efficacy in all stages of ovarian function injury. Based on different perspectives such as inflammatory response and oxidative stress, we explored the therapeutic targets of acupuncture and moxibustion to alleviate ovarian damage, providing a new perspective and experimental basis for clinical acupuncture and moxibustion to mitigate the reproductive toxicity of chemotherapy in women.